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KMID : 0377619730250060695
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Korean Jungang Medical Journal
1973 Volume.25 No. 6 p.695 ~ p.700
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The Studies of Component and Pharmacologic Action on Dianthus sinensis L.
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Abstract
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The component and pharmacologic action on Dianthus sinensis L. were investigated as follows:
1) The components of Dianthus sinensis L. were suggested 8 kind of components by means of thin layer chromatography and paper chromatography. The one of them were suggested as a steroidal saponin by means of IR-spectrum and Liebermann-Burchard, Salkowiski, SbC13 reaction.
2) Blood sugar levels of normal rabbits administered with sample, no significant variation were detected.
3) Blood sugar levels of the alloxan-hyperglycemic rabbits were significantly decreased by administration of the extracted samples.
4) The S-GPT and S-GOT activities of normal rabbits intravenously administered with alloxan (80 mg/kg) after 24 hours were markedly increased.
5) The increased S-GPT and S-GOT activities of the alloxanizated rabbits were significantly decreased after 11 days by oral administration of the extracted samples.
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